Associate Scientist CAR T and TCR Biology

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

The CAR T and TCR Biology team in the Immuno-Oncology Cell Therapy Thematic Research Center has an opening for a highly motivated and creative Associate Scientist with a dedication to discovery and development of novel engineered CAR T and eTCR T cell therapeutics for the treatment of cancer. The successful candidate will have experience setting up in vitro functional assays to measure T cell function: including proliferation, cytokine production, phenotypic analysis and cytotoxic activity. Flow cytometry experience is essential. In addition, this position will work with senior researchers to execute studies, analyze data and communicate results. This position is ideal for the innovative scientist who is driven and passionate about cell therapy in a fast-paced, collaborative environment.

Responsibilities include but are not limited to:

CAR T cell and eTCR T cell generation, expansion, characterization and cryopreservation

CAR T cell and eTCR T cell phenotypic analysis using flow cytometry. In vitro functional evaluation using T cell/Tumor co-culture assays

Cytotoxic activity using IncuCyte

Collaborating with scientists and other researchers to design, perform and optimize in vitro experiments

Maintaining notebooks with detailed documentation of protocols, study designs and results

Perform data analysis and interpretation

Organize findings for effective communication to supervisor and colleagues

Qualifications:

B.S. in biological science, immunology or related discipline with at least 6 years of relevant work experience or M.S. with minimum of 2 years of relevant work experience in T cell biology

Experience with in vitro technologies typically employed to assess T cell functionality including but not limited to MSD, IncuCyte-based assays, multi-parameter flow cytometry for phenotypic characterization of T cells, T cell activation assays, T cell proliferation analysis. Experience with imaging technologies desired but not required

Able to recognize potential problems and recommend/develop appropriate solutions

Ability to work productively as both team member and as individual contributor

Strong communication skills for working with cross-functional teams as well or cross-departmental colleagues

Requires strong organizational skills to ensure thorough and timely documentation of experiments,

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Company info

Bristol-Myers Squibb Company
Website : http://www.bms.com