Job added in hotlist
Applied job
Contract job
90-day-old-job
part-time-job
Recruiter job
Employer job
Expanded search
Apply online not available
View more jobs in Seattle, WA
View more jobs in Washington

Job Details

Principal Scientist Clinical Pharmacokinetics CAR-T

Company name
Bristol-Myers Squibb Company

Location
Seattle, WA, United States

Employment Type
Full-Time

Industry
Sciences, Scientist, Pharmaceutical

Posted on
Mar 21, 2020

Apply for this job






Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Responsibilities include:

Serve as the department lead person for clinical pharmacokinetics (PK) in studies and project teams.

Perform and accountable for non-compartmental PK data analysis

Plan, implement, interpret and report model-based PK and pharmacodynamics (PD) analysis including population PK, PK/PD modeling and simulation, meta-analysis for assigned compounds under clinical development from Phase 1 to 3 and in life cycle management.

Assist in selection of doses and dosing algorithms for clinical development.

Contribute to regulatory documents and meetings; take a lead role in writing and reviewing response to regulatory queries on clinical pharmacology/PK.

Provide input to clinical study designs and PK logistics.

Assist in the development of the statistical analysis plan.

Scientific oversight of CROs with respect to PK and PK/PD tasks.

Qualifications:

Strong quantitative skills with hands-on experience in advanced data analyses, i.e. population PK, PK/PD, and exposure-response analyses.

Competent in the use of various modeling software (NONMEM, SAS, Splus, R, etc.) and standard noncompartmental data analysis software (Phoenix/WiNonlin).

Excellent written and verbal communication skills and demonstrated oral presentation skills.

Ability to work in a cross-functional team environment and to work simultaneously on multiple projects.

Knowledge and experience on clinical database, PK/PD data compilation and manipulation with scripting software of SAS, R and/or Splus.

Familiarity with all stages of drug development from discovery through Phase 4, including experience in the preparation of clinical pharmacology sections of regulatory submissions for IND- and/or NDA-stage projects.

Other Attributes:

Able to anticipate problems at project level.

Proven track record of scientific approach to complex problem solving.

Demonstrate in-depth, scientific-directed, innovative thinking.

Work with multiple studies/programs with moderate to limited oversight

Sets own priorities with some guidance

Keeps manager and key stakeholders informed on programs to assure alignment

Through knowledge of the global drug development process and key deliverable by multiple in collaboration from discovery to commercialization

Through and in depth knowledge of PK/PD and its application and impact on drug development

Thorough understanding of ADME principles in drug development

Good document authoring and review/edit skills

Recognize risk and propose contingency plans.

Acts as a resource to peers, multi-disciplinary teams, and senior management.

Develops constructive relationships across organization to achieve the goals of the function and the business through leadership roles on cross-functional/divisional teams.

Communicates within the larger organization and external community.

Requirements & Education:Advanced degree (Pharm.D. or Ph.D.) or equivalent degree in scientific discipline with a minimum of 8 years’ experience in clinical pharmacology and/or clinical PK/PD and/or pharmacometrics

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Company info

Bristol-Myers Squibb Company
Website : http://www.bms.com

Similar Jobs:
Associate Research Scientist
Location : Seattle, WA
The Allogeneic Cell Therapy and Gene Editing Team is seeking a highly motivated, dynamic and self-driven Associate/Senior Associate Scientist with a dedication to discovery and development of novel engineered CAR T cell therapeuti...
RESEARCH SCIENTIST (Project/Temporary) Req #: 222740 Department: POPULATION HEALTH INITIATIVE Appointing Department Web Address: https://www.washington.edu/populationhealth/ Job Location: Seattle Campus Posting Date: 05/31/2023  C...
Lead Research Scientist, TEAM
Location : Seattle, WA
Lead Research Scientist, TEAM Req #: 223150 Department: INSTITUTE FOR HEALTH METRICS & EVALUATIONS (IHME) Job Location: Remote/Hybrid,  Seattle - Other Job Location Detail: Office is located in Seattle; position is eligible to wor...
By using Employment Crossing, I was able to find a job that I was qualified for and a place that I wanted to work at.
Madison Currin - Greenville, NC
  • All we do is research jobs.
  • Our team of researchers, programmers, and analysts find you jobs from over 1,000 career pages and other sources
  • Our members get more interviews and jobs than people who use "public job boards"
Shoot for the moon. Even if you miss it, you will land among the stars.
ScientistCrossing - #1 Job Aggregation and Private Job-Opening Research Service — The Most Quality Jobs Anywhere
ScientistCrossing is the first job consolidation service in the employment industry to seek to include every job that exists in the world.
Copyright © 2024 ScientistCrossing - All rights reserved. 168 192