Associate Scientist

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

PREREQUISITES

Bachelor's degree in a scientific discipline with at least 6 years work experience or Master's degree with at least 4 years work experience.

Summary/Scope

The Epigenetics group in the Oncogenesis TRC at Bristol-Myers Squibb is seeking a highly motivated and dynamic individual to join the group. The candidate will be expected to design, develop, and execute experiments that include new target validation, identification of biomarkers, elucidation of mechanism of action, epigenetic profiling, and developing assays for cell based screening and compound profiling.

Responsibilities will include, but are not limited to, the following:

Independently design, plan, and execute scientific experiments. Analyze and interpret scientific data, troubleshoot, and suggest new directions. Conduct established assays to confirm hits from primary screens and support SAR. Develop, trouble-shoot, and optimize new cell based functional and biomarker assays. Accurately maintain written reports and organize data. Present projects in team and departmental meetings. Independently review current literature pertaining to oncology, epigenetics, transcriptional regulation, and related assays.

Skills/Knowledge Required :


In-depth knowledge of cancer biology. Familiarity with cancer stem cells and epigenetic mechanisms is highly preferred.
Experience in drug discovery, including developing and running cell-based assays, analyzing screening data, and contributing to hit confirmation efforts.
Experience in molecular and cell biology techniques including cell culture, transfection and transduction techniques (overexpression and silencing), viability assays, functional/phenotypic assays, real time PCR, and immunoblotting.
Experience in running epigenetic profiling assays (ChIP-Seq and ATAC-seq) is a plus.
Proficient in the development of stable cell lines. Knowledge of CRISPR technology is preferred.
Experience in immunocytochemistry is a plus.
Highly motivated, capable of multitasking, intense attention to detail, and innovative.
Excellent time management and organizational skills, strong written and oral communication skills, and is able to think creatively and solve problems.


Functional/Scientific/Technical Skills:


Ability to write protocols and technical reports with precision.
Contributes to design of experiments.
Broadening knowledge and technical skills to increase the department's productivity.
Reviewing literature to get background of a project.
Convey data analysis and interpretation to supervisor and colleagues with clarity and a high level of accuracy. Tasks and Responsibilities:
Assist senior researchers in executing, conducting analysis and reporting results.
Familiarity with literature and internal best practices to identify opportunities to improve productivity and quality of work.
Interprets data, troubleshoots, and recommends corrective actions for routine problems. Discretion/Latitude:
Works relatively independently on assigned tasks.
Makes suggestions on improvements to existing tasks.
Assists colleagues on their field of expertise. Creativity and Problem Solving:
Goes beyond following procedures by seeking opportunities to improve efficiency and productivity.
Fixes unexpected potential problems.
Scientist at this level will differentiate themselves by creativity and innovation. Teamwork and Influence:
Communicates with peers and supervisors.
Contributes to the achievement of workgroup/team goals.
Contributes to some collaborative efforts. Organizational Impact:
Has a direct impact on workgroup performance.
Impact is achieved by driving workgroup results. Behavioral Competencies:
Commitment to quality
Demonstrates adaptability
Develops oneself
Drive for results
Effective speaking
Fosters teamwork
Listens to others
Prepares written communications
Shows work commitment
Uses functional/technical expertise
Works efficientlyBristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives. Company: Bristol-Myers Squibb Req Number: R1526306_EN Updated: 2020-06-16 00:00:00.000 UTC Location: San Diego,California


Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

Company info

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